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CF develops in most patients during the first year of life.

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Most CF patients eventually die from advanced lung disease.

CF also affects, to a lesser extent, the reproductive tract and the sweat glands.

Almost all CF patients begin to experience respiratory symptoms within the first couple of years of life.

They include: In CF patients, nearly all of the pancreatic tissue is destroyed because of the disturbed ion transport, creating a multitude of problems related to pancreatic dysfunction.

Symptoms related to pancreatic insufficiency, especially poor weight gain and bulky, foul-smelling stools, are experienced in over 90 percent of all CF patients.

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